The study examined the determinants of kinesthetic learning style of adult learners in adult literacy centres in Calabar South Local Government Area of Cross Rivers State, Nigeria. The study was guided by five objectives and five research questions. The research design adopted was the descriptive survey design. The population of the study comprises 496 adult learners in 9 adult literacy centres in Calabar South Local Government Area. The 496 learners were sampled through a total sampling technique. The instrument for data collection was a validated self- developed questionnaire titled the determinants of kinesthetic learning style of adult learners in adult literacy centres (DKLSALALC) with a reliability index of 0.76. The data collected for the study were analyzed using the mean and standard deviation. The result of the study revealed that learners’ prior occupational experiences strongly influence their preference to kinesthetic learning style, facilitators’ of interactive instructional methods such as demonstrations, simulations and role-plays greatly enhance learners’ motivation; availability and proper use of instructional materials are vital in promoting kinesthetic learning; conducive physical learning environment that has adequate space, ventilation, lighting and flexible furniture, encourages learners’ engagement in movement-based and collaborative activities; and learners’ motivation and self-efficacy are also crucial for the kinesthetic learning preferences. Based on the findings, the researcher recommended several strategies, including linking activities to learners’ past occupations to enhance engagement and kinesthetic learning and utilizing instructional materials and local resources to support hand-on learning, particularly for government and coordinators.